Abstract #2189

Evaluation of the performance of voxel-wise myocardial perfusion quantification methods using a traceable phantom

Loïc Coquelin¹, Géraldine Ebrard¹, Judith Lehnert², Nadia Smith³, Xenios Milidonis⁴, Tobias Schaeffter^2,5, and Amedeo Chiribiri⁴

¹Department of Mathematics and Statistics, Laboratoire National de Métrologie et d'Essais (LNE), Trappes, France, ²Division of Medical Physics and Metrological Information Technology, Physikalisch-Technische Bundesanstalt (PTB), Braunschweig und Berlin, Berlin, Germany, ³Data Science, National Physical Laboratory (NPL), Teddington, United Kingdom, ⁴Cardiovascular Imaging, King’s College London, London, United Kingdom, ⁵Biomedical Engineering, King’s College London, London, United Kingdom

Assessing and comparing myocardial imaging methodologies require the use of a physical standard. A novel 3D printed cardiac phantom mimicking transmural myocardial perfusion gradients is used in this study, first to evaluate the repeatability of phase contrast MRI (PC-MRI) measurements and then, to compare two common methods for perfusion quantification using dynamic contrast enhanced MRI (DCE-MRI) measurements: the dual bolus and the model-based approach.

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