Abstract #2359

Readout-segmented vs. Single Shot Diffusion MRI for Radiation Therapy Planning in Head and Neck Tumor

Lars Bielak^1,2, Nicole Wiedenmann^2,3, Thomas Lottner¹, Hatice Bunea^2,3, Anca-Ligia Grosu^2,3, and Michael Bock^1,2

¹Dept.of Radiology, Medical Physics, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, ²German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany, ³Department of Radiation Oncology, Medical Center University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany

Image distortion is a major limitation in radiation therapy (RT) planning, especially for diffusion weighed imaging in regions with strong B₀-inhomogeneity. In this study we analyze the improvement of Readout-segmented-EPI over conventional single shot EPI in the geometrically challenging anatomical region of the neck. RS-EPI effectively increases geometric accuracy in head and neck tumor DWI and significantly reduces ghosting artifacts at the cost of a slightly prolonged acquisition time. Therefore it has proven a clear clinical benefit compared to standard SS-EPI.

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