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Abstract #3133

Surfaces Area and Cortical Volume Development of Infant Transverse Temporal Cortex Influenced by Preterm Birth

Xianjun Li1, Jing Xia2, Jian Chen2, Li Wang2, Miaomiao Wang1, Congcong Liu1, Mengxuan Li1, Xiaocheng Wei3, Gang Li2, Dinggang Shen2, and Jian Yang1

1Department of Radiology, the First Affiliated Hospital, Xi’an Jiaotong University, Xi'an, China, 2Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States, 3MR Research China, GE Healthcare, Beijing, China

Development of transverse temporal cortex is essential for speech perception in infants. However, the early morphological development of this cortex has not been fully understood. Additionally, influences of preterm birth on cortical development remain to be investigated. This study assessed cortical development of transverse temporal cortex in preterm and term infants based on surface reconstruction. We found that surface area and cortical volume of transverse temporal cortex underwent rapid changes. Term infants held higher surface area, cortical volume, and asymmetry than preterm infants. These results suggest that preterm birth influences the asymmetry and developmental trajectory of transverse temporal cortex.

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