We attempted to obtain brain high-resolution pseudo-3D (2D multi-slice acquisition with very thin slice thickness) diffusion-weighted echo planar imaging (DW-EPI) using a hybrid compressed sensing and sensitivity encoding (Compressed SENSE) framework (EPICS). pseudo-3D-DWI with EPICS achieved high-resolution (1.15 mm3) isotropic DWI within clinically feasible scan time. Furthermore, EPICS clearly improved the accuracy and robustness of ADC values in high b-value brain DWI with pseudo-3D acquisition without any penalty for scan parameters.
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