Fat plays a central role in the incidence of metabolic syndrome but current MRI biomarkers cannot answer questions about fat cell microstructure. Diffusion-weighted measurements are capable of revealing information about fat tissue microstructure but the required strong diffusion weighting induces scanner table vibrations that eventually lead to measurement errors and artifacts. The purpose of this work was to mitigate vibration artifacts by placing a vibration compensation gradient before the diffusion preparation. The approach was tested in a water-fat phantom and in-vivo in the lower leg of a healthy volunteer.
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