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Abstract #3427

Alterations of brain white matter tracts in children with abnormal intelligence quotient

Yannan Cheng1, Chao Jin2, Xianjun Li2, Congcong Liu2, Miaomiao Wang2, Xiaocheng Wei3, Yuli Zhang2, Fan Wu2, and Jian Yang2

1Department of Radiology, the First Affiliated Hospital, Xi’an Jiaotong University, Xi'an, China, Xi’an, China, 2the First Affiliated Hospital, Xi’an Jiaotong University, Xi'an, China, Xi'an, China, 3MR Research China, GE Healthcare, Bei Jing, People's Republic of China, Bei Jing, China

Studies have shown that brain white matter microstructure is of crucial importance for intelligence. Here, we detailed the alterations of brain white matter tracts in children with abnormal intelligence quotient by comparing the difference of brain white matter tract between the two groups and exploring correlations with intelligence scores based on DTI parameters. Significant differences of ILF, IFO and SLF were found in children with abnormal intelligence quotient. And all these tracts were strongly correlated with intelligence quotient, suggesting the underlying structural origins of lower cognitive function.


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