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Abstract #3577

Powering Up Microstructural Imaging:  assessing cross-metric and cross-tract statistical power on an ultra-strong gradient MRI system

Kristin Koller1, Suryanarayana Umesh Rudapandra1, Maxime Chamberland1, Erika Raven1, Greg D Parker1, Chantal Tax1, Mark Drakesmith1, John C Evans1, Tobias C Wood2, and Derek K Jones1

1Cardiff University Brain Research Imaging Centre, Cardiff University, Cardiff, United Kingdom, 2Department of Neuroimaging, King's College London, London, United Kingdom

We present cross-metric and cross-tract assessment of test-retest repeatability for microstructure measures on an ultra strong gradient MRI scanner (CONNECTOM 3T) in the human brain. We show that several MRI metrics of tissue microstructure are reliable and present relative sample sizes required to provide sufficient statistical power across different white matter pathways and microstructure metrics.

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