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Abstract #3882

Weaker Intra- and Inter-nodal Connectivity of Resting State Networks in Drug-naive Attention-Deficit/Hyperactivity Disorder

Yingxue Gao1, Hailong Li1, Xuan Bu1, Xinyu Hu1, Xiaoxiao Hu1, Lianqing Zhang1, Lu Lu1, Shi Tang1, Kaili Liang1, Yanlin Wang1, Chuang Yang2, and Xiaoqi Huang1

1Department of Radiology, Huaxi Magnetic Resonance Research Centre (HMRRC), Chengdu, China, 2Department of Psychiatry, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

We used group-level independent component analysis (ICA) to investigate functional network connectivity in drug-naïve ADHD children. We extracted eight resting state networks and found that lower intranodal and internodal functional connectivity among executive control, precuneus and default mode networks in ADHD children compared to controls, especially located in prefrontal and parietal regions. This finding may provide new insights into functional connectivity alterations in ADHD children and promote the exploration of functional network connectivity in future researches.

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