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Abstract #3888

Dynamic Functional Connectivity Distinguishes Concussed Youth Based on Symptomology

Raphael Fernandes Casseb1, Alexander S Barton1, Lisa M Langevin1, Alireza Sojoudi1, Keith O Yeates1, and Bradley G Goodyear1

1University of Calgary, Calgary, AB, Canada

Concussion in youth is a growing health issue, and accurate diagnostic, progostic and assessment tools are lacking. In this study, we used a toolbox recently developed by our group (HOCo) to investigate dynamic functional connectivity in fMRI datasets obtained from groups of concussed and orthopedic injured (OI) control subjects. We estimated the proportion of the time that regions of the brain are significantly connected within specific networks. We found that concussed youth with somatic symptoms exhibited more stable connections of the motor and auditory networks, relative to OI subjects and concussed youth with cognitive symptoms.

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