Abstract #4230

Single-voxel short-TR multi-TI multi-TE (SHORTIE) STEAM for water–fat magnetic resonance spectroscopy

Stefan Ruschke¹, Dominik Weidlich¹, Mingming Wu¹, Andreas Hock², and Dimitrios C Karampinos¹

¹Department of Diagnostic and Interventional Radiology, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany, ²Health Systems Philips Schweiz, Zurich, Switzerland

Single-voxel MR spectroscopy (MRS) serves as a reference method in fat containing tissues to probe T₁, T₂ and proton density fat fraction (PDFF). Currently, employed techniques usually rely on long TRs to minimize T₁ bias albeit the prolonged scan time and the reduced SNR efficiency. The purpose of this study is to propose the usage of a short-TR multi-inversion time (TI) multi-TE (SHORTIE) STEAM for the simultaneous assessment of T₁, T₂ and PDFF at reduced scan times when compared to long-TR multi-TI STEAM and long-TR multi-TE STEAM. The agreement between the aforementioned methods was tested in the exemplary application of adipose tissue characterization in the human supraclavicular fossa.

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