Abstract #1606

Quantitation of penumbra volumes in acute ischemic stroke using susceptibility- weighted imaging and mapping

Xiudi Lu¹, Linglei Meng², Yongmin Zhou³, Shaoshi Wang², Miller Fawaz⁴, Meiyun Wang⁵, E. Mark Haacke⁴, Chao Chai⁶, Meizhu Zheng⁷, Jinxia Zhu⁸, Shuang Xia⁶, and Yu Luo³

¹The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China, ²Shanghai Fourth People’s Hospital, Shanghai, China, ³Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine, Shanghai, China, ⁴Wayne State University, Detroit, MI, United States, ⁵Zhengzhou University People’s Hospital, Zhengzhou, China, ⁶Tianjin First Central Hospital, Tianjin, China, ⁷Third Central Hospital of Tianjin, Tianjin, China, ⁸Siemens Healthcare Ltd, Beijing, China

This study aimed to measure ischemic penumbra volumes using susceptibility-weighted imaging and mapping (SWIM). We compared the diagnostic accuracy between SWIvolume-diffusion-weighted imaging (DWI) and SWIASPECTS-DWI mismatches and analyzed the relationships among the SWIvolume-DWI, SWIASPECTS-DWI, and PWI-DWI mismatches and the different parameters and NIHSS. We found that quantitative SWIvolume-DWI mismatch volumes were more accurate than those of the SWIASPECTS-DWI mismatch in being able to evaluate ischemic penumbra. The asymmetrical prominent cortical vein volumes using SWIM showed hypoperfused regions and Tmax >6s volumes, based on perfusion-weighted imaging (PWI). The quantitative SWIvolume-DWI mismatch was highly consistent with the PWI-DWI mismatch.

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