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Abstract #0043

Whole-Body MRI and 11C-Choline PET/CT in Patients with Prostate Cancer

Eschmann S, Pfannenberg C, Aschoff P, Schlemmer H, Mueller-Horvat C, Anastasiadis A, Bares R, Lichy M, Stenzl A, Claussen C, Rodegerts E
University Hospital Tuebingen

The most favourable outcome achievable in patients with prostate cancer is associated with complete tumor resection. For optimizing therapeutic outcome and avoiding unnecessary complications it is a great need to obtain precise information about local tumor extension as well as distant tumor spread particularly to the most common sites, e.g. bone marrow and lymph nodes. Goal of this study is to compare the diagnostic potential of wb-MRI and Cho-PET/CT to detect distant tumor spread in patients with prostate cancer. Our initial data show, that wb-MRI is a very promising diagnostic tool to identify tumor spread in patients with prostate cancer. Particularly bone marrow involvement could better be detected by wb-MRI than by Cho-PET/CT. The synopsis of wb-MRI and Cho-PET results was most favorable with regard to both detection and interpretation of suspicious finding. Regarding the assessment of early lymph node involvement, however, both modalities detected only large metastases (>1cm) and may therefore be limit