Abstract #0042

Voorhees A, Berger K, Goldring R, Chen Q, An J

Simultaneous spirometry and MRI measurements were conducted for the validation of a regional, MRI-based, pulmonary function test. MRI spirometry uses grid-tagged images to dynamically track motion of the lungs during respiration. From displacement maps of the lung parenchyma, regional flow and volume change can be calculated. Results from conventional spirometry, in which the total volumetric air flow rate is measured through the mouth, and lung volume segmentation from MR images were compared with good agreement. This study demonstrates that lung segmentation in conjunction with MRI-based spirometry can be used to assess overall performance, i.e. global function, of the lung.