Steady State Functional Connectivity Modulated by Demand in Working Memory
Gore J, Newton A, Morgan V
Vanderbilt University, Vanderbilt University
Steady state correlations in low frequency BOLD signals have been interpreted as revealing functional connectivity between regions within the human brain. It is still not well understood how they may change as a function of cognitive demand. Our goal is to investigate whether inter-regional correlations in low frequency BOLD signals are functions of demand using the N-back task. Significant differences were found between resting state data and data during task performance. These data confirm that the demand introduced by a higher order cognitive task increase the low frequency correlations between regions known to be involved in the task.