Is the thermal dose a reliable and precise indicator of tissue ablation? A pig liver radiofrequency thermo-ablation under quantitative MR-temperature mapping
Seror O, Quesson B, Lepetit-Coiff M, Trillaud H, LeBail B, Moonen C
Laboratire d'Imagerie Molculaire et Fonctionnelle
Quantitative temperature mapping, associated with continous cumulative thermal dose (TD) assessment, has been suggested for guidance of RF ablation. This study on large animals demonstrates that high quality temperature maps can be obtained on pig liver in vivo on a clinical scanner simultaneously with RF ablation, using appropriate filtering. Apparent lesion dimensions measured on TD maps correlated with histologically determined lesions.