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Abstract #0302

Highly Accelerated IDEAL-SPGR Breast Imaging

McKenzie C, Madhuranthakam A, Gurr D, Yu H, Giaquinto R, Grant A, Sodickson D, Shankaranarayanan A, Joshi S, Menon V, Shimakawa A, Brau A, Steger T, LaRuche S, Farrar N, Dumoulin C, Brittain J, Reeder S, Rofsky N
Beth Israel Deaconess Medical Center, Harvard Medical School

This work evaluates the feasibility of using large acceleration factors (>6x) in combination with the Iterative Decomposition of water and fat with Echo Asymmetry and Least-squares estimation (IDEAL) for dynamic contrast enhanced breast MRI. The major drawback of IDEAL is the additional time needed to acquire three images to produce separate water and fat images. Combining large parallel imaging accelerations with IDEAL techniques eliminates this time penalty. IDEAL with parallel imaging acceleration factors as high as 9.6x was applied to T1w SPGR dynamic contrast enhanced imaging. The advantages of IDEAL over standard fat-suppressed imaging are demonstrated in protocols for breast cancer screening or evaluation.