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Abstract #0624

IDEAL Water-Fat Separation with Simultaneous T2* Estimation

Yu H, Reeder S, McKenzie C, Shimakawa A, Pelc N, Brittain J
GE Healthcare

For three-point water-fat decomposition methods, T2* decay has been assumed to be negligible. However, T2* may be shortened in situations such as in patients with hemochromatosis. It can be difficult to separate water and fat in the presence of shortened T2* or to estimate T2* in the presence of multiple chemical species due to their interference with one another. We propose an algorithm to achieve water-fat separation and T2* estimation simultaneously. Promising results were obtained from phantom studies. This T2*-IDEAL technique has potential applications in quantitative assessment of patients with conditions such as hemochromatosis and fatty infiltration of the liver.