Abstract #0867

Holmes J, Block W, Fain S, O'Halloran R, Jung Y, Peterson E

Hyperpolarized (HP) gas MRI with 3D isotropic resolution will likely improve depiction and analysis of lung structures by reducing partial voluming and providing true cubic voxels for segmentation and measurement. The hypothesis of this work is that multi-echo 3D under-sampled Projection acquisition can provide the desired isotropic resolution in HP gas MRI of the lungs with sufficient SNR efficiency and k-space coverage relative to conventional acquisition techniques. Moreover, the use of multiple echoes per TR will mitigate loss due to RF-decay and reduce under-sampling artifact to improve the attainable resolution within a breath-hold.