Localized Cartilage Assessment with Three-Dimensional dGEMRIC and Quantitative MRI in Patients with Femoroacetabular Impingement
Wilson D, Maedler B, Wilson D, Garbuz D, Duncan C, Eckstein F
University of British Columbia and Vancouver Coastal Health Research Institute
Femoroacetabular impingement (FAI), in which femoral deformities lead to localized damage of the labrum and/or cartilage, has been proposed as a mechanism explaining idiopathic osteoarthritis. To assess localized cartilage degeneration we performed qMRI and 3D-dGEMRIC scans on patients diagnosed with FAI and matched controls. Femoral and acetabular cartilage was segmented to determine cartilage volume and mean/maximum thickness. T1-maps were generated to show the localized glycosaminoglycan distribution within the hip cartilage. Lower cartilage volume was seen in symptomatic patients and regional variation was seen in the dGEMRIC index for all subjects. Our results show the feasibility of comprehensive morphological assessments for hip cartilage and justify making localized dGEMRIC measurements in pathologies such as FAI.