Detection of Pulmonary Emboli by Hyperpolarized Carbon-13 in Pig Model
Petersson J, Golman K, Yu J, Ishii M, Kadlecek S, MacDuffie Woodburn J, Emami K, Rajaei S, Hammond F, Vahdat V, Rizi R
Water-soluble hyperpolarized (HP) 13C compounds represent a new class of MRI contrast agents which may revolutionize metabolic and functional imaging. We present a novel technique for the detection of pulmonary emboli created in a porcine model using the HP MRI contrast agent 2-hydroxyethyl acrylate. Our results indicate that HP 13C MRI angiography is a viable method for detecting pulmonary emboli.