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Abstract #1340

Nonlinear fitting method for the measurements of Regional Alveolar Oxygen Pressure and Oxygen Depletion Rate by Hyperpolarized 3He MRI

Lipson D, Yu J, Ishii M, Kadlecek S, MacDuffie Woodburn J, Emami K, Rajaei S, Hammond F, Vahdat V, Rizi R, Clark T, Brainard B, Gefter W
University of Pennsylvania

The regional alveolar oxygen partial pressure and regional oxygen depletion rate are important functional lung parameters. We present here a new nonlinear fitting technique for measuring these parameters, with a new timing scheme suitable for managing multiple-slice measurements.