Abstract #1509

Pardoe H, Pell G, Abbott D, Jackson G, Berg A

Voxel-based morphometry was used to investigate structural variations in a unique cohort of idiopathic and cryptogenic epilepsy syndromes. Childhood absence epilepsy, Cryptogenic Localization Related Epilepsy and Benign Rolandic Epilepsy syndromes were investigated for gray matter volume decreases. The regions of gray matter volume decrease correlated well with regions of BOLD signal change in idiopathic epilepsies observed in an independent fMRI study.