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Abstract #1779

Quantitative SENSE Spectroscopy of Gliomas at 3T

Ozturk-Isik E, Xu D, Chen A, Crane J, Han E, Vigneron D, Cha S, Chang S, Nelson S
University of California, UCSF/UCB Joint Graduate Group in Bioengineering

SENSE MRSI has been implemented for imaging gliomas at high field, and was quantitatively analyzed in comparison to spectra acquired with elliptical k-space sampling. SENSE spectra reduced the spectral scan time from 37:42 min (R=1) to 9:28 min (R=4) for a 16x16x8 array, and resulted in better spatial resolution than the elliptical k-space sampling acquired with comparable scan time. Our results indicated that both SENSE and elliptical k-space spectra resulted in similar spectral patterns over the PRESS box, and were able to distinguish spectra of tumor from normal tissue.