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Abstract #2018

A Novel Autocorrelation Method for Measuring the Thickness Anisotropy Tensor of Trabecular Bone

Vasilic B, Wehrli F
University of Pennsylvania Medical Center

The full width at half maximum of the autocorrelation function of cancellous bone images provides a good estimate of trabecular thickness. The thickness anisotropy tensor can be calculated from k-space data acquired in MRI. Through numerical experiments on micro-CT data we show that by anisotropic sampling one can substantially improve the resolution with which the principal values of the anisotropy tensor are measured without significantly sacrificing accuracy or sensitivity.