Bi-exponential Characterization of T2 Relaxation Decay in an Engineered Osteogenic Tissue Model
Othman S, Magin R, Xu H, hong L
University of Illinois at Chicago
In this in vitro MR study of tissue engineered bone, the T2 relaxation (at 500 MHz) of developing osteogenic implants was measured over a 4-week period. Both mono-exponential and bi-exponential fits to the T2 relaxation time were investigated. The data show that for the early time points investigated, both a fast and a slow component to the spin-spin relaxation was present, suggesting increasing tissue heterogeneity with bone morphogenesis.