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Abstract #2019

Bi-exponential Characterization of T2 Relaxation Decay in an Engineered Osteogenic Tissue Model

Othman S, Magin R, Xu H, hong L
University of Illinois at Chicago

In this in vitro MR study of tissue engineered bone, the T2 relaxation (at 500 MHz) of developing osteogenic implants was measured over a 4-week period. Both mono-exponential and bi-exponential fits to the T2 relaxation time were investigated. The data show that for the early time points investigated, both a fast and a slow component to the spin-spin relaxation was present, suggesting increasing tissue heterogeneity with bone morphogenesis.