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Abstract #2021

High Resolution 3D Brain MR-Elastography

Green M, Sinkus R, Bilston L
Prince of Wales Medical Research Institute

High resolution in-vivo measurement of the viscoelastic properties of the brain has been achieved via 3D steady-state MR-Elastography at 3T. Several parameters within the MR sequencing and the mathematical reconstruction have been optimised to produce mechanical waves which are efficiently coupled into the skull allowing maximum amplitude in the centre of the brain whilst maintaining good signal to noise. Quantified results agree well with rheological measurements made on bovine and porcine brain tissue in the literature and they also show very good correlation with anatomical structures such as grey matter, white matter and ventricles.