Water Mapping of the Whole Brains of Infants Using an FSE Sequence at 3.0 T
Dong Z, Liu F, Kangarlu A, Peterson B, Peterson B
Columbia University, New York State Psychiatric Institute
Water content is an important variable in brain development because it is closely related to the progress of myelination in the central nervous system of humans.A number of methods and applications for measuring water content in the brain with MRI have been reported in the last decade. Several have been quantitative techniques; however, to our best knowledge, they have all been performed in adults or children only, not in infants. Here we present a preliminary study of mapping water content quantitatively in the brains of healthy infants using multi-slice images acquired with a fast spin echo (FSE) pulse sequence.