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Abstract #2323

Semi-automatic 3D Segmentation and CNR Measurement of Mn2+ Enhanced Optical Nerve in Adult Rats

Olsen , Kovalev V, Brekken C, Haraldseth O, Goa P, Thuen M, Petrou M
Sr-Trndelag University College, Norwegian University of Science and Technology

The purpose of this project was to develop an objective method of calculating Contrast-to-Noise Ratio (CNR) profiles from 3D MRI data of the Mn2+ enhanced optic nerve, based on minimal user intervention. We present a robust and objective a method for calculating the CNR profile of the Mn2+ enhanced optical nerve based on objective image post processing with few user interactions. The method traces the nerve centre, segments the nerve from the eye and calculate the CNR profile with a user defined spatial resolution. Even though the method is dedicated for a specific application it is of general interest.