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Abstract #2329

Effects of the Dietary Fatty Acids on Manganese-enhanced Magnetic Resonance Imaging (MEMRI)

Kuo Y, Herlihy A, So P, Bell J
Hammersmith Hospital, Imperial College London, Faculty of Medicine, School of Medicine, Kaohsiung Medical University

Dietary supplementation of the omega-3 fatty acids have been shown to have beneficial effects on the cardiovascular system in human and animal, but the effect on the brain is not conclusive. MEMRI has been successfully used to study brain structures and activity, but the effect of the long-term dietary intervention on MEMRI is still unknown. In this study, we have performed MEMRI to evaluate the effects of dietary fatty acids on the murine brain. The results suggest MEMRI is able to detect the effects of dietary fatty acids on the brain, with dietary low fish oil supplement showing neuroprotective effect.