Removal of Sideband Modulations in 1H MRS without Solvent Suppression
Ozdemir M, De Asseler Y, Lemahieu I, De Deene Y
The majority of in vivo proton spectra utilize solvent suppression so as to reduce the dynamic range for the detection of signals originating from low-concentrated metabolites. We previously showed that it is possible to perform absolute quantification of proton spectra without water suppression in a single measurement. Nonetheless, the quality of the unsuppressed water spectra is deteriorated by the water sidebands caused by time varying modulation of the main magnetic field due to mechanical vibrations of the gradient coils. In this work, we proposed a method to remove the gradient-induced sideband modulations and verified the method in a phantom study.