The DICOM Standard: Is Twelve Bits Enough?
Sakaie K, Lowe M
The Cleveland Clinic Foundation
The DICOM image storage standard allocates 12 bits per pixel to represent image intensities, even though current hardware typically allows at least 16 bits of resolution. Quantitative imaging requiring large dynamic range may suffer errors due to the 12-bit limit. Simulations and measurements indicate that typical fMRI and DTI experiments can suffer appreciable errors due to the bit-resolution limit associated with the DICOM standard.