Determination of the Variability of fMRI Responses Using Deconvolution Analysis
Chawla N, Biswal B
University of Medicine & Dentistry of New Jersey (UMDNJ)
A large number of statistical tests (including t-test, cross-correlation, F-test, deconvolution, etc.) are currently used in functional Magnetic Resonance Imaging (fMRI) to localize and quantify task-induced signal changes. It is currently assumed that fMRI time-points are stationary i.e., signal characteristics do not change over time. In this study, time-varying signal characteristics of fMRI signal response were investigated using Impulse response function. Substantial variation in the activation map was obtained for bilateral finger tapping paradigm. The proposed method can be extended to study variation between different experiments, and can also be used to detect habituations, or learning effects.