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Abstract #2523

Inversion recovery in the presence of radiation damping - implications for evaluating contrast agents

Eykyn T, Tung W, Payne G, Leach M
Institute of Cancer Research, Royal Marsden NHS Foundation Trust

Relaxation measurements performed at high magnetic field may be adversely affected by the influence of radiation damping in concentrated samples such as 1H in water. We consider how the measured value of T1 is affected by this phenomenon for a gadolinium-doped water sample and for an un-doped water sample. A method employing pulsed field gradients is proposed for suppressing this effect and the method is validated for measuring the relaxivity of the commercial contrast agent GdDTPA.