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Abstract #2660

WIMP: Self-Navigating Magnetization Transfer Pool Mapping with Stimulated Echoes

Newbould R, Bammer R, Liu C, Ropele S
Stanford University

A new quantitative magnetization transfer (MT) scheme has been proposed which needs neither complex multi-parametric models nor wide-band MT RF pulses. This sequence is used with both un-navigated and navigated spiral acquisitions. Random phase accumulation from diffusion-like preparatory gradients, combined with the need for two separate acquisitions, sensitizes the results to even miniscule compliant patient motions, and has previously precluded the use of a multi-shot acquisition. Motion and phase correction via the variable-density navigated spiral technique allows much higher resolution multi-shot acquisitions, and greatly improves the resultant bound pool fraction (BPF) images.