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Abstract #2669

Magnetization Transfer Imaging in distinguishing Early and Adult Onset Schizophrenia in drug-naive first-episode patients

Gong Q, Huang X, Wang Y, Lui S, Ouyang L, Deng W, Tang H, Li T, Song B, Zhou X, Sluming V, Maclean S
West China Hospital of Sichuan University

Early-onset schizophrenia (EOS) is thought to be a unique subtype of schizophrenia compared with its adult-onset schizophrenia (AOS) counterpart. We applied whole brain voxel-wised analysis of magnetization transfer ratio (MTR) to explore the difference of the cerebral tissue in first-episode drug-naive patients with EOS versus AOS. The result showed that there were significant differences of MTR in cerebral regions of EOS which distinguished itself from AOS in MT imaging.