Estimation of Blood Magnetization for quantification of Arterial Spin Labeling Signal
van de Ven K, Petersen E, Golay X
National Neuroscience Institute, Eindhoven University of Technology
A new method is proposed to get an estimate of the average blood magnetization in a user-independent way, using the QUASARASL sequence. T1t and M0t are calculated from measured signals with a Look-Locker based method. Monte Carlo simulations are provided in order to test the robustness of the method. The results of the Monte Carlo simulations show that it is possible to get back to T1t and M0t and measurements on volunteers also give reliable results for the T1t values in the brain. This method is believed to be better compared to the traditional ROI based methods.