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Abstract #2718

Myelination and Axonal Integrity of Spinal Cord Sensory and Motor Pathways Revealed by Diffusion Tensor MRI

Jones C, Smith S, McDonald J, Calabresi P, Mori S, van Zijl P, Farrell J
Kennedy Krieger Institute, Johns Hopkins University School of Medicine

Diffusion tensor images were acquired on the cervical spinal cord from C2 to C6 in four volunteers. Fiber tracking was done in the left and right lateral and dorsal columns and tract-specific fractional anisotropy, apparent diffusion coefficient (ADC) and magnetization transfer (MT) contrast were quantified per slice. The measures had left-right symmetry for both pathways. There was a small statistical difference in ADC between the lateral and dorsal columns.