Method of Measuring Diffusion Anisotropy and Diffusion Gradient Simultaneously with DTI
Michigan State University
Water diffusion in tissues is generally inhomogeneous and anisotropic due to spatial-location variation (gradient) and spatial-direction variation (anisotropy) of tissue structures. Diffusion anisotropy is measured by DTI. A newly derived theoretical relationship between diffusion gradient and the echo signal in a diffusion-weighted spin-echo pulse sequence establishes the theoretical basis for measuring the diffusion gradient. This paper presents a method of simultaneously measuring diffusion anisotropy and diffusion gradient.