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Abstract #2931

Dynamic Contrast Enhanced MRI as a priori predictor of response in head and neck squamous cell carcinoma: Initial Analysis

Stambuk H, Shukla-Dave A, Karimi S, Su Y, Pfister D, Wang Y, Koutcher J, Lee N
Memorial Sloan-Kettering Cancer Center

Squamous cell carcinoma of the head and neck (HNSCC) is the fifth most common malignancy in the world and the survival rates have remained relatively unchanged over the past 3 decades. Today with many treatment options available, it is important to have an a priori method to stratify good risk and poor risk categories to improve outcome and quality of life. The present study was designed to assess whether pretreatment DCE-MRI changes can reliably predict response. DCE-MRI was performed in 17 patients prior to chemo-radiation therapy. The initial results suggest that DCE-MRI may prove to be a useful a priori predictor of response in HNSCC patients.