Investigation of Flip Angle Dependence in Spatially Resolved 2D Correlated MR Spectroscopy
Banakar S, Thomas A, Binesh N
LABIOMED at Harbor-UCLA
Flip-angle dependence of the last 90 degree rf pulse used for slice-selection as well as coherence transfer in localized 2D COSY was investigated using phantom solutions. The experimental results were compared with theoretical simulations. A phantom containing six metabolites at physiological concentrations was investigated to record 2D L-COSY spectra at different flip-angles of the last rf pulse. Two MRI scanners (1.5T and 3T) with respective quadrature extremity coils were used. 2D spectral simulation was carried out using GAMMA library. Our preliminary findings indicate that the maxima of the 2D cross and diagonal peaks occur at 90 and 180 degrees, respectively.