In vivo 31P(1H) EchoPlanar Spectroscopic Imaging of the Human Brain
Ulrich M, Wokrina T, Bachert P, Ende G
Central Institute of Mental Health
Echo-Planar Spectroscopic Imaging (EPSI) is one of the fastest in vivo spectroscopic imaging (SI) techniques. Although this method was implemented for various 1H-MRS applications, EPSI of phosphorous-containing metabolites in the human brain has, to our knowledge, never been considered so far. Here we present the development of eight NOE enhanced 31P-(1H) EPSI sequences with short TE, which permit 2-D SI of the human brain providing good quality high resolution 31P-spectra with different spectral widths. These results convincingly show that 31P-EPSI as a very fast and robust data acquisition method to allow for functional MRS studies.