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Abstract #3135

Diffusion Anisotropy Reflects Progression of Spinal Cord Contusion Injury in Mice

Kim J, Song S
Washington University

Relative anisotropy (RA) was examined using both in vivo and ex vivo DTI on normal and contusion injured mouse spinal cords. Ex vivo RA of ventrolateral white matter from normal mice is not statistically different over a SNR range from 40 130. At SNR of 50, in vivo and ex vivo RA measurements were not statistically different. Both in vivo and ex vivo measured RA reflects the temporal and spatial progression of white matter damage after contusion injury in mice.