Functional spectroscopy: A new experimental method in exploring the Glutamate-Glutamine cycle in the human brain
Specht K, Grner R, Barndon R, van Wageningen H, Hugdahl K, Ersland L
University of Bergen
In this study, single-voxel H1-MR Spectroscopy (TE 35ms) was used in 20 humans in order to explore changes in the concentration of metabolites in the sensory-motor system, when the explored subject was performing a motor task. That spectrum was compared to a spectrum, measured during rest. The results showed significant differences in the concentration of Glutamate, Glucose and Lactate. By contrast, a reference region in the occipital lobe didnt showed any significant changes under the same conditions.