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Abstract #3406

Functional and connectivity asymmetry observed in the visual system of an infant with white matter lesions on MRI

Dresner M, Counsell S, Srinivasan L, Edwards A, Cowan F, Raafat R, Allsop J, Rutherford M, Hajnal J
Imperial College London

We present our findings of combined fMRI and probabilistic tractography of the visual system in a 2 year old infant who was born preterm and developed bilateral periventricular leukomalacia and right sided periventricular haemorrhagic infarction. These lesions were evident on serial, conventional MRI. fMRI and DTI obtained at 3 Tesla demonstrated asymmetrical activation in the visual cortex and connectivity distributions in the optic radiations, with diminished activation and connectivity distributions in the hemisphere with the porencephalic cyst.