Abstract #3408

Detre J, Wang J, Ichord R, Silvestre D, Zimmerman R, Licht D, Agner S

Arterial spin labeling (ASL) perfusion is a useful tool in imaging cerebral blood flow (CBF) in adults with cerebrovascular disease. In addition, ASL has been shown to have unique advantages in the pediatric population. In this study, we assess the hemodynamic status in children with acute arterial ischemic stroke (AIS) due to M1 segment MCA stenosis using pulsed ASL (PASL) perfusion imaging. This application demonstrates feasibility and utility of PASL in acute and longitudinal AIS imaging in pediatrics.