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Abstract #3576

Myocardial Perfusion Recovery after Percutaneous Coronary Intervention Using First-pass Contrast-Enhanced MRI

Su M, Chu W, Tseng W, Wu C, Yang K
Institute of Biomedical Engerening, National Yang-Ming University

Percutaneous coronary intervention (PCI) for patients with chronic stable angina aims at restoration of blood flow in the stenotic coronary arteries. Traditional coronary angiography and nuclear tracer imaging have serious limitations for judging the magnitude and timing of recovered myocardial perfusion after PCI. In this study, we performed first-pass contrast-enhanced myocardial perfusion MRI at 3T MR system to determine the timing and magnitude of perfusion recovery by evaluating the change in myocardial perfusion reserve (MPR) index in a serial follow-up. We found that MPR index in ischemic segments was restored as early as 24 hours after successful PCI. The improvement of myocardial perfusion lasted at least for one week and tended to persist at one month following PCI.