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Abstract #0007

Compressed Sensing for Hyperpolarized 3He 3D ADC Measurements

Lise Vejby Sgaard1, Torsten Dorniok1, Frederik Hengstenberg1,2, Sergei Karpuk3, Jrgen Vestbo2, Per keson1, Peter Magnusson1

1Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital, Hvidovre, Denmark; 2Department of Cardiology and Respiratory Medicine, Copenhagen University Hospital, Hvidovre, Denmark; 3Institute of Physics, University of Mainz, Germany

The feasibility of applying compressed sensing methods to hyperpolarized 3He apparent diffusion coefficient measurements was investigated. Fully sampled 3D k-space data from one healthy subject and three COPD patients were undersampled and reconstructed by compressed sensing methods. We expect that the method can be used to either decrease scan time (breath-hold) or increase spatial resolution which will be especially important in longitudinal studies of lung disease progression.