Abstract #0008

Parallel Acquisition as a Key for Rapid High Resolution 3He-ADC Imaging

Maxim V. Terekhov¹, Julien Rivoire¹, Florian M. Meise¹, Davide Santoro¹, Wolfgang G. Schreiber¹

¹Department of Diagnostic and Interventional Radiology, Section of Medical Physics, Mainz University Medical School, Mainz, Germany

Apparent Diffusion Coefficient (ADC) of hyperpolarized 3He-gas in lungs is a proven method of non-invasive probing the integrity of the lungs microstructure. The essential problem of efficiency of 3He-ADC-imaging as the diagnostic tool is the poor localisation of integrity defects due to low spatial resolution of ADC-maps. The purpose of current work is to demonstrate the possibilities, provided by the phased-array parallel acquisition (32ch) for improving the efficiency of 3He ADC-measurements including creating full-3D ADC-maps. The second important task is making comparison of different methods of reconstruction the undersampled imaging datasets (e.g. mSENSE and GRAPPA) to get optimal quality ADC-image.