Abstract #0073

Evaluation of Cartilage T2 Using Loading in Situ MRI in Early Osteoarthritis with Hip Dysplasia

Takashi Nishii¹, Toshiyuki Shiomi², Hisashi Tanaka³, Youichi Yamazaki⁴, Kenya Murase⁴, Takashi Sakai², Masaki Takao², Hideki Yoshikawa², Nobuhiko Sugano¹

¹Department of Orthopaedic Medical Engineering, Osaka University Medical School, Osaka, Japan; ²Department of Orthopaedic Surgery, Osaka University Medical School, Osaka, Japan; ³Department of Radiology, Osaka University Medical School, Osaka, Japan; ⁴Department of Medical Physics & Engineering, Osaka University Medical School, Osaka, Japan

Cartilage T2 with use of loading in situ MR imaging (50% of body weight) was evaluated in 9 patients with hip dysplasia and 9 normal volunteers, for evaluation of cartilage pressure distribution in vivo. There was significant decrease of T2 by loading at the outer zone of the acetabular cartilage and inner zone of the femoral cartilage in dysplastic hips (p<0.05). Loading in situ MR imaging with T2 assessment may allow biomechanical assessment of pathological conditions related to localized stress concentration and have prognostic significance for osteoarthritic changes in hip dysplasia.