Daniel Kim1, Jens H. Jensen1, Ed X. Wu2, Sujit S. Sheth3, Gary M. Brittenham3
1Center for Biomedical Imaging and Radiology, NYU Langone Medical Center, New York, NY, USA; 2Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong; 3Pediatrics and Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA
MRI provides a means to non-invasively assess tissue iron concentration by exploiting the paramagnetic effects of iron on T2 or T2*. The most widely used method is T2* imaging is sensitive to non-iron related magnetic field (B0) inhomogeneities, which can confound T2* measurements within the whole heart and liver. An alternative method is T2 imaging, but they are generally performed during free breathing with respiratory gating due to their low data acquisition efficiency. The purpose of this study was to develop a breath-hold fast spin echo (FSE) sequence for fast and accurate imaging of myocardial and hepatic T2.
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